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Funnel chart showing the AI drug discovery pipeline for rentosertib: 79 molecules synthesized narrowing to 1 preclinical candidate, then Phase I, Phase IIa with 71 patients, and Phase III with 320 patients. The AI-discovered drug rentosertib is the first fully AI-originated molecule to reach Phase III.

AI-discovered drug rentosertib enters Phase III trial

Rentosertib, an AI-discovered TNIK inhibitor for IPF, enters Phase III with 320 patients. It is the first fully AI-originated drug to reach late-stage trials.

Lars Cornelissen · Jul 8, 2026